We are interested in the merger of high-throughput experimentation (HTE) with data science to drive next-generation chemical synthesis. Using state-of-the-art automated technologies, the HTE platform provides an opportunity for rapid reaction development, novel reaction discovery and prediction of chemical reactivity.
Our group works with state-of-the-art equipment to explore application of our methodologies to high-throughput reaction development, including a Mosquito high-throughput pipetting robot, a brand-new triple quad mass spectrometer with multiple reaction monitoring, and bespoke constructions to enable e.g. irradiation of microwell plates. With that, dozens of reaction conditions can be screened in parallel to rapidly identify best candidates.