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75. J. Am. Chem. Soc., 2019, 141, 8426, Streamlined synthesis of C(sp3)–H rich N-heterospirocycles enabled by visible-light-mediated photocatalysis

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69. Chem. Sci., 2018, 10, 83, Mechanistic Investigation into the C(sp3)–H Acetoxylation of Morpholinones

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68. Nature, 2018, 561, 522, Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

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67. Chem. Sci., 2018, 9, 7628, Diastereoselective C−H Carbonylative Annulation of Aliphatic Amines: A Rapid Route to Functionalized γ-Lactams

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66. Angew. Chem. Int. Ed., 2018, 57, 3178, Selective Reductive Elimination at Alkyl Pd(IV) via Dissociative Ligand Ionization Enables Catalytic C(sp3)−H Amination to Azetidines

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65. Chem. Sci., 2017, 8, 8198, The α-Tertiary Amine Motif Drives Remarkable Selectivity for Palladium-Catalyzed Carbonylation of Methylene C−H Bonds

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64. Angew. Chem. Int. Ed., 2017, 56, 11958, Selective Palladium(II)-Catalyzed Carbonylation of β Methylene C−H Bonds in Aliphatic Amines

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63. J. Am. Chem. Soc., 2017, 139, 9160, Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol  Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts

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62. Chem. Sci., 2017, 8, 3586, Ligand-Assisted Palladium-Catalyzed C−H Alkenylation of Aliphatic Amines for the Synthesis of Functionalized Pyrrolidines

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61. Chem. Sci., 2017, 8, 2588, Cobalt-Catalyzed C−H Carbonylative Cyclisation of Aliphatic Amides

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60. J. Am. Chem. Soc., 2017, 139, 1412, Palladium-Catalyzed Enantioselective C−H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

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59. Science, 2016, 354, 851, A General Catalytic β-C−H Carbonylation of Aliphatic Amines to β-Lactams

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​

58. J. Am. Chem. Soc., 2016, 138, 13183, Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts towards the Synthesis of P-Chiral Phosphines

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57. Angew. Chem. Int. Ed., 2016, 55, 9024, Continuous-Flow Synthesis and Derivitization of Aziridines through Palladium-Catalyzed C(sp3)−H Activation

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56. Chem. Sci., 2016, 7, 2706, The Total Synthesis of K-252c (Staurosporinone) via a Sequential C−H Functionalization Strategy

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55. Synlett, 2016, 27, 116, Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy

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54. Angew. Chem. Int. Ed., 2015, 54, 15840, Ligand-Enabled Catalytic C−H Arylation of Aliphatic Amines by a Four-Membered Ring Cyclopalladation Pathway

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53. Nat. Chem., 2015, 7, 1009, A Steric-Tethering Approach Enables Palladium-Catalyzed C−H Activation of Primary Amino Alcohols

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52. J. Am. Chem. Soc., 2015, 137, 10362, Mechanistic Insights Into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C−H Activation

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51. J. Am. Chem. Soc., 2015, 137, 7986, Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts

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50. Angew. Chem. Int. Ed., 2015, 54, 7857, Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional Syn-1,3-Diol Derivatives

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49. Angew. Chem. Int. Ed., 2015, 54, 5451, A Concise and Scalable Strategy for the Total Synthesis of Dictyodendrin B Based on Sequential C−H Functionalization 

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48. Chem. Sci., 2015, 6, 1277, A Counterion Triggered Arylation Strategy Using Diaryliodonium Fluorides 

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47. Angew. Chem. Int. Ed., 2014, 53, 13498, Gram-Scale Enantioselective Formal Synthesis of Morphine Through an Ortho-Para Oxidative Phenolic Coupling Strategy

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46. J. Am. Chem. Soc., 2014, 136, 8851, Cu-Catalyzed Cascades to Carbocycles: Union of Diaryliodonium Salts with Alkenes or Alkynes Exploiting Remote Carbocations

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45. Nature, 2014, 510, 129, Palladium-Catalyzed C−H Activation of Aliphatic Amines to Give Strained Nitrogen Heterocycles

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44. J. Am. Chem. Soc., 2013, 135, 12532, Copper-Catalyzed Carboarylation of Alkynes via Vinyl Cations

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43. Angew. Chem. Int. Ed., 2013, 52, 9284, Copper-Catalyzed Intramolecular Electrophilic Carbofunctionalization of Allylic Amides

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42. Angew. Chem. Int. Ed., 2013, 52, 5799, Copper-Catalyzed Arylative Meyer-Schuster Rearrangement of Propargylic Alcohols to Complex Enones Using Diaryliodonium Salts

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41. J. Am. Chem. Soc., 2013, 135, 5322, Copper-Catalyzed Electrophilic Carbofunctionalization of Alkynes to Highly Functionalized Tetrasubstituted Alkenes

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40. J. Am. Chem. Soc., 2013, 135, 3772, Organocatalytic C−H Bond Arylation of Aldehydes to Bis-Heteroaryl Ketones

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39. Angew. Chem. Int. Ed., 2012, 51, 9288, Chemical Synthesis of Aspidosperma Alkaloids Inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products

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38. J. Am. Chem. Soc., 2012, 134, 10773, Copper-Catalyzed Alkene Arylation with Diaryliodonium Salts

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37. J. Am. Chem. Soc., 2011, 133, 13778, Enantioselective α-Arylation of N-Acyloxazolidinones With Copper(II)-Bisoxazoline Catalysts and Diaryliodonium Salts

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36. Chem. Sci., 2011, 2, 1487, Catalytic Enantioselective Assembly of Complex Molecules Containing Embedded Quaternary Stereogenic Centres from Simple Anisidine Derivatives

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35. Chem. Soc. Rev., 2011, 40, 1885, Recent Development in Natural Product Synthesis Using Metal-Catalyzed C−H Bond Functionalization

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34. Angew. Chem. Int. Ed., 2011, 50, 1076, Palladium(II)-Catalyzed C−H Bond Arylation of Electron-Deficient Arenes at Room Temperature

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33. Angew. Chem. Int. Ed., 2011, 50, 463, Copper(II)-Catalyzed Meta-Selective Direct Arylation of α-Aryl Carbonyl Compounds

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32. Angew. Chem. Int. Ed., 2011, 50, 458, A Highly Para-Selective Copper(II)-Catalyzed Direct Arylation of Aniline and Phenol Derivatives

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31. Chem. Sci., 2011, 2, 312, Amine Directed Pd(II)-Catalyzed C−H Bond Functionalization Under Ambient Conditions

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30. Tetrahedron, 2010, 66, 6429, Alkynes to (E)-Enolates Using Tandem Catalysis: Stereoselective Anti-Aldol and Syn-[3,3]-Rearrangement Reactions

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29. Science, 2009, 323, 1593, A Meta-Selective Copper-Catalyzed C−H Bond Arylation

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28. J. Am. Chem. Soc., 2008, 130, 8172, Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

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27. Angew. Chem. Int. Ed., 2008, 47, 3004, Synthesis of Rhazinicine by a Metal-Catalyzed C−H Bond Functionalization Strategy

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26. J. Am. Chem. Soc., 2008, 130, 404, An Enantioselective Organocatalytic Oxidative Dearomatization Strategy

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25. Chem. Rev., 2007, 107, 5596, Recent Developments in the Use of Catalytic Asymmetric Ammonium Enolates in Chemical Synthesis 

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24. Drug Discov. Today, 2007, 12, 8, Enantioselective Organocatalysis Review

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23. Angew. Chem. Int. Ed., 2006, 45, 6024, Enantioselective Catalytic Intramolecular Cyclopropanation Using Modified Cinchona Alkaloid Organocatalysts

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22. J. Am. Chem. Soc., 2006, 128, 2528, Mild Aerobic Oxidative Palladium(II)-Catalyzed C−H Bond Functionalization: Regioselective and Switchable C−H Alkenylation and Annulation of Pyrroles

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21. Angew. Chem. Int. Ed., 2006, 45, 2116, Organocatalytic Sigmatropic Reactions: Development of a [2,3]-Wittig Rearrangement Through Secondary Amine Catalysis

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20. Angew. Chem. Int. Ed., 2005, 44, 3125, Palladium-Catalyzed Intermolecular Alkenylation of Indoles via Solvent-Controlled Regioselective C−H Functionalization

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19. Angew. Chem. Int. Ed., 2004, 43, 4641, Enantioselective Organocatalytic Cyclopropanation via Ammonium Ylides

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18. Angew. Chem. Int. Ed., 2004, 43, 2681, An Intramolecular Organocatalytic Cyclopropanation Reaction 

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17. Angew. Chem. Int. Ed., 2003, 42, 828, Organic-Catalyst-Mediated Cyclopropanation Reaction

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Postdoctoral Studies: Professor Steven Ley

16. J. Org. Chem., 2006, 7, 2715, Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems to Generate Protected 1,3-Dicarbonyl Compounds 

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15. Synlett, 2005, 13, 2031, Synthesis of  the EF Fragment of Spongistatin 1

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14. Angew. Chem. Int. Ed., 2005, 44, 5433, Total Synthesis of Spongistatin 1: Exploiting the Latent Pseudo-Symmetry

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13. Org. Lett., 2003, 5, 4819, Synthesis of C-1-C-28 ABCD Unit of Spongistatin 1

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12. Org. Lett., 2003, 5, 4815, A Practical and Efficient Synthesis of the C-16-C-28 Spiroketal Fragment (CD) of the Spongistatins

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11. Org. Lett., 2003, 5, 1147, Addition of Dithiols to Bis-Ynones: Development of a Versatile Platform for the Synthesis of Polyketide Natural Products

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10. Org. Biomol. Chem., 2003, 1, 15, Development of β-Keto 1,3-Dithianes as Versatile Intermediates for Organic Synthesis

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Postdoctoral Studies: Professor Amos Smith

9. J. Am. Chem. Soc., 2003, 125, 14435, Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Epoxides, Epichlorohydrin and Vinyl Epoxides: Efficient, Rapid and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis

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8. J. Am. Chem. Soc., 2002, 124, 14516, Dithiane Additions to Vinyl Epoxides: Steric Control Over SN2 and SN2' Manifolds

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PhD Studies: Dr Jonathan Spencer

7. Chem. Eur. J., 2006, 12, 949, Novel Anti-Markovnikov Regioselectivity in the Wacker Reaction of Styrenes

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6. J. Org. Chem., 2002, 67, 4627, Convenient Preparation of Pure Trans-Arylalkenes via Palladium(II)-Catalyzed Isomerization of the Cis-Alkenes

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5. Chem. Comm., 2001, 0, 1844, Evidence that the Availability of an Allylic Hydrogen Governs the Regioselectivity of the Wacker Oxidation

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4. Org. Lett., 2001, 3, 25, Derailing the Wacker Oxidation: Development of a Palladium-Catalyzed Amidation Reaction

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3. Org. Lett., 2000, 2, 1049, Selective Hydrogenolysis of Novel Benzyl Carbamate Protecting Groups

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2. Tetrahedron Lett., 1999, 40, 1803, Preferential Hydrogenolysis of NAP Esters Provides a New Orthogonal Protecting Group Strategy for Carboxylic Acids

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1. J. Org. Chem., 1998, 63, 4172, Rational Design of Benzyl Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Catalytic Hydrogenolysis

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