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67. Chem. Sci., 2018, 9, 7628, Diastereoselective C−H Carbonylative Annulation of Aliphatic Amines: A Rapid Route to Functionalized γ-Lactams

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65. Chem. Sci., 2017, 8, 8198, The α-Tertiary Amine Motif Drives Remarkable Selectivity for Palladium-Catalyzed Carbonylation of Methylene C−H Bonds

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64. Angew. Chem. Int. Ed., 2017, 56, 11958, Selective Palladium(II)-Catalyzed Carbonylation of β Methylene C−H Bonds in Aliphatic Amines

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63. J. Am. Chem. Soc., 2017, 139, 9160, Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol  Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts

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62. Chem. Sci., 2017, 8, 3586, Ligand-Assisted Palladium-Catalyzed C−H Alkenylation of Aliphatic Amines for the Synthesis of Functionalized Pyrrolidines

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61. Chem. Sci., 2017, 8, 2588, Cobalt-Catalyzed C−H Carbonylative Cyclisation of Aliphatic Amides

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60. J. Am. Chem. Soc., 2017, 139, 1412, Palladium-Catalyzed Enantioselective C−H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

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59. Science, 2016, 354, 851, A General Catalytic β-C−H Carbonylation of Aliphatic Amines to β-Lactams

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58. J. Am. Chem. Soc., 2016, 138, 13183, Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts towards the Synthesis of P-Chiral Phosphines

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57. Angew. Chem. Int. Ed., 2016, 55, 9024, Continuous-Flow Synthesis and Derivitization of Aziridines through Palladium-Catalyzed C(sp3)−H Activation

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56. Chem. Sci., 2016, 7, 2706, The Total Synthesis of K-252c (Staurosporinone) via a Sequential C−H Functionalization Strategy

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55. Synlett, 2016, 27, 116, Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy

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54. Angew. Chem. Int. Ed., 2015, 54, 15840, Ligand-Enabled Catalytic C−H Arylation of Aliphatic Amines by a Four-Membered Ring Cyclopalladation Pathway

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53. Nat. Chem., 2015, 7, 1009, A Steric-Tethering Approach Enables Palladium-Catalyzed C−H Activation of Primary Amino Alcohols

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52. J. Am. Chem. Soc., 2015, 137, 10362, Mechanistic Insights Into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C−H Activation

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51. J. Am. Chem. Soc., 2015, 137, 7986, Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts

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50. Angew. Chem. Int. Ed., 2015, 54, 7857, Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional Syn-1,3-Diol Derivatives

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49. Angew. Chem. Int. Ed., 2015, 54, 5451, A Concise and Scalable Strategy for the Total Synthesis of Dictyodendrin B Based on Sequential C−H Functionalization 

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48. Chem. Sci., 2015, 6, 1277, A Counterion Triggered Arylation Strategy Using Diaryliodonium Fluorides 

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47. Angew. Chem. Int. Ed., 2014, 53, 13498, Gram-Scale Enantioselective Formal Synthesis of Morphine Through an Ortho-Para Oxidative Phenolic Coupling Strategy

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46. J. Am. Chem. Soc., 2014, 136, 8851, Cu-Catalyzed Cascades to Carbocycles: Union of Diaryliodonium Salts with Alkenes or Alkynes Exploiting Remote Carbocations

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45. Nature, 2014, 510, 129, Palladium-Catalyzed C−H Activation of Aliphatic Amines to Give Strained Nitrogen Heterocycles

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44. J. Am. Chem. Soc., 2013, 135, 12532, Copper-Catalyzed Carboarylation of Alkynes via Vinyl Cations

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43. Angew. Chem. Int. Ed., 2013, 52, 9284, Copper-Catalyzed Intramolecular Electrophilic Carbofunctionalization of Allylic Amides

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42. Angew. Chem. Int. Ed., 2013, 52, 5799, Copper-Catalyzed Arylative Meyer-Schuster Rearrangement of Propargylic Alcohols to Complex Enones Using Diaryliodonium Salts

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41. J. Am. Chem. Soc., 2013, 135, 5322, Copper-Catalyzed Electrophilic Carbofunctionalization of Alkynes to Highly Functionalized Tetrasubstituted Alkenes

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40. J. Am. Chem. Soc., 2013, 135, 3772, Organocatalytic C−H Bond Arylation of Aldehydes to Bis-Heteroaryl Ketones

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39. Angew. Chem. Int. Ed., 2012, 51, 9288, Chemical Synthesis of Aspidosperma Alkaloids Inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products

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38. J. Am. Chem. Soc., 2012, 134, 10773, Copper-Catalyzed Alkene Arylation with Diaryliodonium Salts

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37. J. Am. Chem. Soc., 2011, 133, 13778, Enantioselective α-Arylation of N-Acyloxazolidinones With Copper(II)-Bisoxazoline Catalysts and Diaryliodonium Salts

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36. Chem. Sci., 2011, 2, 1487, Catalytic Enantioselective Assembly of Complex Molecules Containing Embedded Quaternary Stereogenic Centres from Simple Anisidine Derivatives

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34. Angew. Chem. Int. Ed., 2011, 50, 1076, Palladium(II)-Catalyzed C−H Bond Arylation of Electron-Deficient Arenes at Room Temperature

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33. Angew. Chem. Int. Ed., 2011, 50, 463, Copper(II)-Catalyzed Meta-Selective Direct Arylation of α-Aryl Carbonyl Compounds

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32. Angew. Chem. Int. Ed., 2011, 50, 458, A Highly Para-Selective Copper(II)-Catalyzed Direct Arylation of Aniline and Phenol Derivatives

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31. Chem. Sci., 2011, 2, 312, Amine Directed Pd(II)-Catalyzed C−H Bond Functionalization Under Ambient Conditions

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30. Tetrahedron, 2010, 66, 6429, Alkynes to (E)-Enolates Using Tandem Catalysis: Stereoselective Anti-Aldol and Syn-[3,3]-Rearrangement Reactions

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29. Science, 2009, 323, 1593, A Meta-Selective Copper-Catalyzed C−H Bond Arylation

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28. J. Am. Chem. Soc., 2008, 130, 8172, Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

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27. Angew. Chem. Int. Ed., 2008, 47, 3004, Synthesis of Rhazinicine by a Metal-Catalyzed C−H Bond Functionalization Strategy

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26. J. Am. Chem. Soc., 2008, 130, 404, An Enantioselective Organocatalytic Oxidative Dearomatization Strategy

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25. Chem. Rev., 2007, 107, 5596, Recent Developments in the Use of Catalytic Asymmetric Ammonium Enolates in Chemical Synthesis 

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24. Drug Discov. Today, 2007, 12, 8, Enantioselective Organocatalysis Review

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23. Angew. Chem. Int. Ed., 2006, 45, 6024, Enantioselective Catalytic Intramolecular Cyclopropanation Using Modified Cinchona Alkaloid Organocatalysts

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22. J. Am. Chem. Soc., 2006, 128, 2528, Mild Aerobic Oxidative Palladium(II)-Catalyzed C−H Bond Functionalization: Regioselective and Switchable C−H Alkenylation and Annulation of Pyrroles

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21. Angew. Chem. Int. Ed., 2006, 45, 2116, Organocatalytic Sigmatropic Reactions: Development of a [2,3]-Wittig Rearrangement Through Secondary Amine Catalysis

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20. Angew. Chem. Int. Ed., 2005, 44, 3125, Palladium-Catalyzed Intermolecular Alkenylation of Indoles via Solvent-Controlled Regioselective C−H Functionalization

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19. Angew. Chem. Int. Ed., 2004, 43, 4641, Enantioselective Organocatalytic Cyclopropanation via Ammonium Ylides

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18. Angew. Chem. Int. Ed., 2004, 43, 2681, An Intramolecular Organocatalytic Cyclopropanation Reaction 

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17. Angew. Chem. Int. Ed., 2003, 42, 828, Organic-Catalyst-Mediated Cyclopropanation Reaction

DOI:10.1002/anie.200390222

Postdoctoral Studies: Professor Steven Ley

16. J. Org. Chem., 2006, 7, 2715, Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems to Generate Protected 1,3-Dicarbonyl Compounds 

DOI:10.1021/jo052514s

15. Synlett, 2005, 13, 2031, Synthesis of  the EF Fragment of Spongistatin 1

DOI:10.1055/s-2005-871960

14. Angew. Chem. Int. Ed., 2005, 44, 5433, Total Synthesis of Spongistatin 1: Exploiting the Latent Pseudo-Symmetry

DOI:10.1002/anie.200502008

13. Org. Lett., 2003, 5, 4819, Synthesis of C-1-C-28 ABCD Unit of Spongistatin 1

DOI:10.1021/ol035849+

12. Org. Lett., 2003, 5, 4815, A Practical and Efficient Synthesis of the C-16-C-28 Spiroketal Fragment (CD) of the Spongistatins

DOI:10.1021/ol035848h

11. Org. Lett., 2003, 5, 1147, Addition of Dithiols to Bis-Ynones: Development of a Versatile Platform for the Synthesis of Polyketide Natural Products

DOI:10.1021/ol034248f

10. Org. Biomol. Chem., 2003, 1, 15, Development of β-Keto 1,3-Dithianes as Versatile Intermediates for Organic Synthesis

DOI:10.1039/B208982C

Postdoctoral Studies (with Professor Amos Smith)

9. Amos B. Smith, Suresh M. Pitram, Armen M. Boldi, Matthew J. Gaunt, Chris Sfouggatakis, William H. Moser

Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Epoxides, Epichlorohydrin and Vinyl Epoxides: Efficient, Rapid and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis

J. Am. Chem. Soc. 2003, 125, 14435 (10.1021/ja0376238)

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8. Amos B. Smith, Suresh M. Pitram, Matthew J. Gaunt, Sergey A. Kozmin

Dithiane Additions to Vinyl Epoxides: Steric Control Over SN2 and SN2' Manifolds

J. Am. Chem. Soc. 2002, 124, 14516 (10.1021/ja0283100)

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PhD Studies (with Dr Jonathan Spencer)

7. Joseph A. Wright, Matthew J. Gaunt, Jonathan B. Spencer

Novel Anti-Markovnikov Regioselectivity in the Wacker Reaction of Styrenes

Chem. Eur. J. 2006, 12, 949 (10.1002/chem.200400644)

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6. Jinquan Yu, Matthew J. Gaunt, Jonathan B. Spencer

Convenient Preparation of Pure Trans-Arylalkenes via Palladium(II)-Catalyzed Isomerization of the Cis-Alkenes

J. Org. Chem. 2002, 67, 4627 (10.1021/jo015880u)

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5. Matthew J. Gaunt, Jinquan Yu, Jonathan B. Spencer

Evidence that the Availability of an Allylic Hydrogen Governs the Regioselectivity of the Wacker Oxidation

Chem. Comm. 2001, 1844 (10.1039/B103066N)

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4. Matthew J. Gaunt, Jonathan B. Spencer

Derailing the Wacker Oxidation: Development of a Palladium-Catalyzed Amidation Reaction

Org. Lett. 2001, 3, 25 (10.1021/ol0066882)

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2. Matthew J. Gaunt, Carlos E. Boschetti, Jinquan Yu, Jonathan B. Spencer

Preferential Hydrogenolysis of NAP Esters Provides a New Orthogonal Protecting Group Strategy for Carboxylic Acids 

Tetrahedron Lett. 1999, 40, 1803 (10.1016/S0040-4039(99)00014-3)

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1. Matthew J. Gaunt, Jinquan Yu, Jonathan B. Spencer

Rational Design of Benzyl Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Cata-lytic Hydrogenolysis 

J. Org. Chem. 1998, 63, 4172 (10.1021/jo980823v)