76. Nils J. Flodén, Aaron Trowbridge, Darren Willcox, Scarlett M. Walton, Yongjoon Kim, Matthew J. Gaunt

Streamlined synthesis of C(sp3)–H rich N-heterospirocycles enabled by visible-light-mediated photocatalysis

J. Am. Chem. Soc. 2019, 141, 8426 (110.1021/jacs.9b03372)

70. Cornelia S. Buettner, Darren Willcox, Ben G. N. Chappell, Matthew J. Gaunt

Mechanistic Investigation into the C(sp3)–H Acetoxylation of Morpholinones

Chem. Sci., 2018, 10, 83 (10.1039/C8SC03434F)

69. Aaron Trowbridge, Dominik Reich, Matthew Gaunt

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

Nature, 2018, 561, 522 (10.1038/s41586-018-0537-9)

68. Zhuang Mao Png, Jaime R. Cabrera-Pardo, Jorge Peiró Cadahíaa, Matthew J. Gaunt

Diastereoselective C−H Carbonylative Annulation of Aliphatic Amines: A Rapid Route to Functionalized γ-Lactams

Chem. Sci., 2018, 9, 7628 (10.1039/C8SC02855A)

67. Manuel Nappi, Chuan He, William G. Whitehurst, Ben G. N. Chappell, Matthew J. Gaunt

Selective Reductive Elimination at Alkyl Pd(IV) via Dissociative Ligand Ionization Enables Catalytic C(sp3)−H Amination to Azetidines

Angew. Chem. Int. Ed., 2018, 57, 3178 (10.1002/anie.201800519)

66. Kirsten F. Hogg, Aaron Trowbridge, Andres Alvarez-Pérez, Matthew J. Gaunt 

The α-Tertiary Amine Motif Drives Remarkable Selectivity for Palladium-Catalyzed Carbonylation of Methylene C−H Bonds

Chem. Sci., 2017, 8, 8198 (10.1039/C7SC03876C)

65. Jaime R. Cabrera‐Pardo, Aaron Trowbridge, Manuel Nappi, Kyohei Ozaki, Matthew J. Gaunt

Selective Palladium(II)-Catalyzed Carbonylation of β Methylene C−H Bonds in Aliphatic Amines

Angew. Chem. Int. Ed., 2017, 56, 11958 (10.1002/anie.201706303)

64. Daniel H. Lukamto, Matthew J. Gaunt 

Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol  Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts

J. Am. Chem. Soc., 2017, 139, 9160 (10.1021/jacs.7b05340)

63. Chuan He, Matthew J. Gaunt 

Ligand-Assisted Palladium-Catalyzed C−H Alkenylation of Aliphatic Amines for the Synthesis of Functionalized Pyrrolidines

Chem. Sci., 2017, 8, 3586 (10.1039/C7SC00468K)

62. Patrick Williamson, Alicia Galván, Matthew J. Gaunt

Cobalt-Catalyzed C−H Carbonylative Cyclisation of Aliphatic Amides

Chem. Sci., 2017, 8, 2588 (10.1039/C6SC05581H)

61. Adam P. Smalley, James D. Cuthbertson, Matthew J. Gaunt  

Palladium-Catalyzed Enantioselective C−H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands

J. Am. Chem. Soc., 2017, 139, 1412 (10.1021/jacs.6b12234)

60. Darren Willcox, Ben G. N. Chappell, Kirsten F. Hogg, Jonas Calleja, Adam P. Smalley, Matthew J. Gaunt

A General Catalytic β-C−H Carbonylation of Aliphatic Amines to β-Lactams

Science, 2016, 354, 851 (10.1126/science.aaf9621)

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59. Rodolphe Beaud, Robert J. Phipps, Matthew J. Gaunt

Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts towards the Synthesis of P-Chiral Phosphines

J. Am. Chem. Soc., 2016, 138, 13183 (10.1021/jacs.6b09334)

58. Jacek Zakrzewski, Adam P. Smalley, Mikhail A. Kabeshov, Matthew J. Gaunt, Alexei A. Lapkin

Continuous-Flow Synthesis and Derivitization of Aziridines through Palladium-Catalyzed C(sp3)−H Activation

Angew. Chem. Int. Ed., 2016, 55, 9024 (10.1002/anie.201602483)

57. , James C. Fox, Ruth E. Gilligan, Andrew K. Pitts, H. R. Bennett,  Matthew J. Gaunt

The Total Synthesis of K-252c (Staurosporinone) via a Sequential C−H Functionalization Strategy

Chem. Sci., 2016, 7, 2706 (10.1039/C5SC04399A)

56. Alice E. Williamson, Tifelle Ngouansavanh, Robert D. M. Pace, Anna E. Allen, James D. Cuthbertson, Matthew J. Gaunt 

Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy

Synlett, 2016, 27, 116 (10.1055/s-0035-1560377)

55. Chuan He, Matthew J. Gaunt

Ligand-Enabled Catalytic C−H Arylation of Aliphatic Amines by a Four-Membered Ring Cyclopalladation Pathway

Angew. Chem. Int. Ed., 2015, 54, 15840 (10.1002/anie.201508912)

54.  Jonas Calleja, Daniel Pla, Timothy W. Gorman, Victoriano Domingo, Benjamin Haffemayer, Matthew J. Gaunt 

A Steric-Tethering Approach Enables Palladium-Catalyzed C−H Activation of Primary Amino Alcohols

Nat. Chem., 2015, 7, 1009 (10.1038/nchem.2367)

53. Adam P. Smalley, Matthew J. Gaunt 

Mechanistic Insights Into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C−H Activation

J. Am. Chem. Soc., 2015, 137, 10362 (10.1021/jacs.5b05529)

52. Elise Cahard, Henry P. J. Male, Matthieu Tissot, Matthew J. Gaunt

Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts

J. Am. Chem. Soc., 2015, 137, 7986(10.1021/jacs.5b03937)

51. Dean Holt, Matthew J. Gaunt

Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional Syn-1,3-Diol Derivatives

Angew. Chem. Int. Ed., 2015, 54, 7857 (10.1002/anie.201501995)

50. Andrew K. Pitts, Fionn O'Hara, Robert H. Snell, Matthew J. Gaunt

A Concise and Scalable Strategy for the Total Synthesis of Dictyodendrin B Based on Sequential C−H Functionalization 

Angew. Chem. Int. Ed., 2015, 54, 5451 (10.1002/anie.201500067)

49. Louis Chan, Andrew McNally, Qiao Y. Toh, Abraham Mendoza, Mathew J. Gaunt

A Counterion Triggered Arylation Strategy Using Diaryliodonium Fluorides 

Chem. Sci., 2015, 6, 1277 (10.1039/C4SC02856B)

48. Matthieu Tissot, Robert J. Phipps, Catherine Lucas, Rafael M. Leon, Robert D. M. Pace, Tifelle Ngouansavanh, Matthew J. Gaunt

Gram-Scale Enantioselective Formal Synthesis of Morphine Through an Ortho-Para Oxidative Phenolic Coupling Strategy

Angew. Chem. Int. Ed., 2014, 53, 13498 (10.1002/anie.201408435)

47. Fengzhi Zhang, Shoubhik Das, Andrew J. Walkinshaw, Alicia Casitas, Michael Taylor, Marcos G. Suero, Matthew J. Gaunt

Cu-Catalyzed Cascades to Carbocycles: Union of Diaryliodonium Salts with Alkenes or Alkynes Exploiting Remote Carbocations

J. Am. Chem. Soc., 2014, 136, 8851 (10.1021/ja504361y)

46. Andrew McNally, Benjamin Haffemayer, Beatrice S. L. Collins, Matthew J. Gaunt 

Palladium-Catalyzed C−H Activation of Aliphatic Amines to Give Strained Nitrogen Heterocycles

Nature, 2014, 510, 129 (10.1038/nature13389)

45. Andrew J. Walkinshaw, Wenshu Xu, Marcos G. Suero, Matthew J. Gaunt

Copper-Catalyzed Carboarylation of Alkynes via Vinyl Cations

J. Am. Chem. Soc., 2013, 135, 12532 (10.1021/ja405972h)

44. Elise Cahard, Nadine Bremeyer, Matthew J. Gaunt 

Copper-Catalyzed Intramolecular Electrophilic Carbofunctionalization of Allylic Amides

Angew. Chem. Int. Ed., 2013, 52, 9284 (10.1002/anie.201303724)

43. Beatrice S. L. Collins, Marcos G. Suero, Matthew J. Gaunt 

Copper-Catalyzed Arylative Meyer-Schuster Rearrangement of Propargylic Alcohols to Complex Enones Using Diaryliodonium Salts

Angew. Chem. Int. Ed., 2013, 52, 5799 (10.1002/anie.201301529)

42., Marcos G. Suero, Elliott D. Bayle, Beatrice S. L. Collins, Matthew J. Gaunt

Copper-Catalyzed Electrophilic Carbofunctionalization of Alkynes to Highly Functionalized Tetrasubstituted Alkenes

J. Am. Chem. Soc., 2013, 135, 5322 (10.1021/ja401840j)

41. Qiao Yan Toh, Andrew McNally, Silvia Vera, Nico Erdmann, Matthew J. Gaunt

Organocatalytic C−H Bond Arylation of Aldehydes to Bis-Heteroaryl Ketones

J. Am. Chem. Soc., 2013, 135, 3772 (10.1021/ja400051d)

40. Lindsay McMurray, Elizabeth M. Beck, Matthew J. Gaunt

Chemical Synthesis of Aspidosperma Alkaloids Inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products

Angew. Chem. Int. Ed., 2012, 51, 9288 (10.1002/anie.201204151)

39. Robert J. Phipps, Lindsay McMurray, Stefanie Ritter, Hung A. Duong, Matthew J. Gaunt
Copper-Catalyzed Alkene Arylation with Diaryliodonium Salts

J. Am. Chem. Soc., 2012, 134, 10773 (10.1021/ja3039807)

38. Aurélien Bigot, Alice E. Williamson, Matthew J. Gaunt

Enantioselective α-Arylation of N-Acyloxazolidinones With Copper(II)-Bisoxazoline Catalysts and Diaryliodonium Salts

J. Am. Chem. Soc., 2011, 133, 13778 (10.1021/ja206047h)

37. Rafael Leon, Anup Jawalekar, Thomas Rederta, Matthew J. Gaunt   

Catalytic Enantioselective Assembly of Complex Molecules Containing Embedded Quaternary Stereogenic Centres from Simple Anisidine Derivatives

Chem. Sci., 2011, 2, 1487 (10.1039/C1SC00218J)

36. Lindsay McMurray, Fionn O'Haraa, Matthew J. Gaunt 

Recent Development in Natural Product Synthesis Using Metal-Catalyzed C−H Bond Functionalization

Chem. Soc. Rev., 2011, 40, 1885 (10.1039/C1CS15013H)

35. Matthew J. Tredwell, Moises Gulias, Nadine Bremeyer, Carin C. C. Johansson, Beatrice S. L. Collins, Matthew J. Gaunt

Palladium(II)-Catalyzed C−H Bond Arylation of Electron-Deficient Arenes at Room Temperature

Angew. Chem. Int. Ed., 2011, 50, 107610.1002/anie.201005990

34. Hung A. Duong, Ruth E. Gilligan, Michael L. Cooke, Robert J. Phipps, Matthew J. Gaunt

Copper(II)-Catalyzed Meta-Selective Direct Arylation of α-Aryl Carbonyl Compounds

Angew. Chem. Int. Ed., 2011, 50, 463 (10.1002/anie.201004704)

33. Claire‐Lise Ciana, Robert J. Phipps, Jochen R. Brandt, Falco‐Magnus Meyer, Matthew J. Gaunt

A Highly Para-Selective Copper(II)-Catalyzed Direct Arylation of Aniline and Phenol Derivatives

Angew. Chem. Int. Ed., 2011, 50, 458 (10.1002/anie.201004703)

32. Benjamin Haffemayer, Moises Guliasa, Matthew J. Gaunt

Amine Directed Pd(II)-Catalyzed C−H Bond Functionalization Under Ambient Conditions

Chem. Sci., 2011, 2, 312 (10.1039/C0SC00367K)

31. Neil P. Grimster, Donna A. A. Wilton, Louis K. M. Chan, Christopher R. A. Godfrey, Clive Green, Dafydd R. Owen, Matthew J.Gaunt

 Alkynes to (E)-Enolates Using Tandem Catalysis: Stereoselective Anti-Aldol and Syn-[3,3]-Rearrangement Reactions

Tetrahedron, 2010, 66, 6429 (10.1016/j.tet.2010.05.045)

30. Robert J. Phipps, Matthew J. Gaunt

A Meta-Selective Copper-Catalyzed C−H Bond Arylation

Science, 2009, 323, 1593 (10.1126/science.1169975)

29. James A. Jordan-Hore, Carin C. C. Johansson, Moises Gulias, Elizabeth M. Beck, Matthew J. Gaunt

Oxidative Pd(II)-Catalyzed C−H Bond Amination to Carbazole at Ambient Temperature

J. Am. Chem. Soc., 2008, 130, 16184 (10.1021/ja806543s)

28. Robert J. Phipps, Neil P. Grimster, Matthew J. Gaunt

Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

J. Am. Chem. Soc., 2008, 130, 8172 (10.1021/ja801767s)

27. Carin C. C. Johansson, Nadine Bremeyer, Steven V. Ley, Dafydd R. Owen, Stephen C. Smith, Matthew J. Gaunt

Synthesis of Rhazinicine by a Metal-Catalyzed C−H Bond Functionalization Strategy

Angew. Chem. Int. Ed., 2008, 47, 3004 (10.1002/ange.200602129)

26. Ngoc T. Vo, Robert D. M. Pace, Fionn O'Har, Matthew J. Gaunt

An Enantioselective Organocatalytic Oxidative Dearomatization Strategy

J. Am. Chem. Soc., 2008, 130, 40410.1021/ja077457u

25. Carin C. C. Johansson, Matthew J. Gaunt
Recent Developments in the Use of Catalytic Asymmetric Ammonium Enolates in Chemical Synthesis 

Chem. Rev., 2007, 107, 5596 (10.1021/cr0683764)

24. Carin C. C. Johansson, Andy McNally, Ngoc T. Vo, Matthew J. Gaunt

Enantioselective Organocatalysis Review

Drug Discov. Today, 2007, 12, 8 (10.1016/j.drudis.2006.11.004)

23. Carin C. C. Johansson, Nadine Bremeyer, Steven V. Ley, Dafydd R. Owen, Stephen C. Smith, Matthew J. Gaunt

Enantioselective Catalytic Intramolecular Cyclopropanation Using Modified Cinchona Alkaloid Organocatalysts

Angew. Chem. Int. Ed., 2006, 45, 6024 (10.1002/anie.200602129)

22. Elizabeth M. Beck, Neil P. Grimster, Richard Hatley, Matthew J. Gaunt 

Mild Aerobic Oxidative Palladium(II)-Catalyzed C−H Bond Functionalization: Regioselective and Switchable C−H Alkenylation and Annulation of Pyrroles

J. Am. Chem. Soc., 2006, 128, 2528 (10.1021/ja058141u)

21. Andrew McNally, Brian Evans, Matthew J. Gaunt

Organocatalytic Sigmatropic Reactions: Development of a [2,3]-Wittig Rearrangement Through Secondary Amine Catalysis

Angew. Chem. Int. Ed., 2006, 45, 2116 (10.1002/anie.200504301)

20. Neil P. Grimster, Carolyn Gauntlett, Christopher R. A. Godfrey, Matthew J. Gaunt

Palladium-Catalyzed Intermolecular Alkenylation of Indoles via Solvent-Controlled Regioselective C−H Functionalization

Angew. Chem. Int. Ed., 2005, 44, 3125 (10.1002/anie.200500468)

19. Charles D. Papageorgiou, Maria A. Cubillo de Dios, Steven V. Ley, Matthew J. Gaunt  

Enantioselective Organocatalytic Cyclopropanation via Ammonium Ylides

Angew. Chem. Int. Ed., 2004, 43, 4641 (10.1002/anie.200460234)

18. Nadine Bremeyer, Stephen C. Smith, Steven V. Ley, Matthew J. Gaunt

 An Intramolecular Organocatalytic Cyclopropanation Reaction 

Angew. Chem. Int. Ed., 2004, 43, 2681 (10.1002/anie.200454007)

17. Charles D. Papageorgiou, Steven V. Ley, Matthew J. Gaunt

Organic-Catalyst-Mediated Cyclopropanation Reaction

Angew. Chem. Int. Ed., 2003, 42, 828 (10.1002/anie.200390222)

Postdoctoral Studies: Professor Steven Ley

16. Helen F. Sneddon,Alexandra van den Heuvel, Anna K. H. Hirsch, Richard A. Booth, David M. Shaw, Matthew J. Gaunt, Steven V. Ley

Double Conjugate Addition of Dithiols to Propargylic Carbonyl Systems to Generate Protected 1,3-Dicarbonyl Compounds 

J. Org. Chem., 2006, 7, 2715 (10.1021/jo052514s)

15. Shigeru Kawahara, Matthew J. Gaunt, Alessandra Scolaro, Shigeo Yamanoi, Steven V. Ley

Synthesis of  the EF Fragment of Spongistatin 1

Synlett, 2005, 13, 2031 (10.1055/s-2005-871960)

14. Matthew Ball, Matthew J. Gaunt, David F. Hook, Alan S. Jessiman, Shigeru Kawahara, Paolo Orsini,  Alessandra Scolaro, Adam C. Talbot, Huw R. Tanner, Shigeo Yamanoi, Steven V. Ley

Total Synthesis of Spongistatin 1: Exploiting the Latent Pseudo-Symmetry

Angew. Chem. Int. Ed., 2005, 44, 5433 (10.1002/anie.200502008)

13. Matthew J. Gaunt, Alan S. Jessiman, Paolo Orsini, Huw R. Tanner, David F. Hook, Steven V. Ley

Synthesis of C-1-C-28 ABCD Unit of Spongistatin 1

Org. Lett., 2003, 5, 4819 (10.1021/ol035849+)

12. Matthew J. Gaunt, David F. Hook, Huw R. Tanner, Steven V. Ley

A Practical and Efficient Synthesis of the C-16-C-28 Spiroketal Fragment (CD) of the Spongistatins

Org. Lett., 2003, 5, 4815 (10.1021/ol035848h)

11. Helen F. Sneddon, Matthew J. Gaunt, Steven V. Ley

Addition of Dithiols to Bis-Ynones: Development of a Versatile Platform for the Synthesis of Polyketide Natural Products

Org. Lett., 2003, 5, 1147 (10.1021/ol034248f)

10. Matthew J. Gaunt, Helen F. Sneddon, Peter R. Hewitt, Paolo Orsini, David F. Hooka, Steven V. Ley 

Development of β-Keto 1,3-Dithianes as Versatile Intermediates for Organic Synthesis

Org. Biomol. Chem., 2003, 1, 15 (10.1039/B208982C)

Postdoctoral Studies (with Professor Amos Smith)

9. Amos B. Smith, Suresh M. Pitram, Armen M. Boldi, Matthew J. Gaunt, Chris Sfouggatakis, William H. Moser

Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Epoxides, Epichlorohydrin and Vinyl Epoxides: Efficient, Rapid and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis

J. Am. Chem. Soc. 2003, 125, 14435 (10.1021/ja0376238)

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8. Amos B. Smith, Suresh M. Pitram, Matthew J. Gaunt, Sergey A. Kozmin

Dithiane Additions to Vinyl Epoxides: Steric Control Over SN2 and SN2' Manifolds

J. Am. Chem. Soc. 2002, 124, 14516 (10.1021/ja0283100)

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PhD Studies (with Dr Jonathan Spencer)

7. Joseph A. Wright, Matthew J. Gaunt, Jonathan B. Spencer

Novel Anti-Markovnikov Regioselectivity in the Wacker Reaction of Styrenes

Chem. Eur. J. 2006, 12, 949 (10.1002/chem.200400644)

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6. Jinquan Yu, Matthew J. Gaunt, Jonathan B. Spencer

Convenient Preparation of Pure Trans-Arylalkenes via Palladium(II)-Catalyzed Isomerization of the Cis-Alkenes

J. Org. Chem. 2002, 67, 4627 (10.1021/jo015880u)

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5. Matthew J. Gaunt, Jinquan Yu, Jonathan B. Spencer

Evidence that the Availability of an Allylic Hydrogen Governs the Regioselectivity of the Wacker Oxidation

Chem. Comm. 2001, 1844 (10.1039/B103066N)

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4. Matthew J. Gaunt, Jonathan B. Spencer

Derailing the Wacker Oxidation: Development of a Palladium-Catalyzed Amidation Reaction

Org. Lett. 2001, 3, 25 (10.1021/ol0066882)

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2. Matthew J. Gaunt, Carlos E. Boschetti, Jinquan Yu, Jonathan B. Spencer

Preferential Hydrogenolysis of NAP Esters Provides a New Orthogonal Protecting Group Strategy for Carboxylic Acids 

Tetrahedron Lett. 1999, 40, 1803 (10.1016/S0040-4039(99)00014-3)

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1. Matthew J. Gaunt, Jinquan Yu, Jonathan B. Spencer

Rational Design of Benzyl Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Cata-lytic Hydrogenolysis 

J. Org. Chem. 1998, 63, 4172 (10.1021/jo980823v)